Current support
- Artificially engineered exosomes for gene editing in the brain. Funding source: NIH/Common Fund - Targeted Genome Editor Delivery (TARGETED) Challenge Phase I. Role: PI.
- Controllable In Vivo Genome Editing for Immune-Checkpoint Blockade in Solid Tumors. Funding source: NIH/NIBIB (R01EB026893). Role: PI.
- Magnetic nanocomplexes-induced immunomodulation for fracture healing. Funding source: NIH/NIAMS(R21AR078447). Role: PI.
- Precise in vivo gene editing of HSPC for the treatment of genetic hematologic diseases. Funding source: NIH/NHLBI (R21HL166178). Role: PI.
- Role of SMPDL3B in obesity-associated non-alcoholic fatty liver disease. Funding source: NIH/NIDDK (R01DK131876). Role: Co-I (PI: Shuxia Wang).
- Point-of-care Functional Spectroscopy Platform and Novel Ratio-metric Algorithms for Near Real-time Metabolic and Vascular Characterization of Biological Models in Vivo. Funding source: NIH/NIDCR (R01DE031998). Role: Co-I (PI: Caigang Zhu).
- Development of a 3D microfluidic electroporation technology for advancing cell therapy. Funding source: University of Kentucky Igniting Research Collaborations (IRC). Role: Co-I (PI: Guigen Zhang).
Past support
- Precise in vivo gene editing of HSPC for the treatment of genetic hematologic diseases. Funding source: University of Kentucky Igniting Research Collaborations (IRC). Role: PI. Duration: 07/01/2022-12/31/2022
- Development of a Nano-Enabled Platform for Combination Immunotherapy. Funding source: NIGMS/COBRE (5P20GM121327-05, pilot grant). Role: PI. Duration: 01/01/2021-12/31/2021
- Development of magnetic nanoparticle heating for long-term organ preservation. Electron Microscopy Assistance. Funding source: Kentucky Biomedical Research Infrastructure Network (KBRIN). Role: PI. Duration: 02/2020-04/2021
- Optimization of Electroporation-Assisted Nanoparticle Uptake in a Pancreatic Nude Mouse Model. Funding source: Radiological Society of North America (RSD1717). Role: co-I (PI: Derek West). Duration: 06/01/2018-05/31/2019